Publications
MOLECULAR GLUES | TARGETED PROTEIN DEGRADATION | AI IN DRUG DISCOVERY
Molecular Glues:
PubMed | August 2022
1. Methods to characterize and discover molecular degraders in cells
PubMed | July 2022
2. Molecular glues: The adhesive connecting targeted protein degradation to the clinic
PubMed | March 2022
3. Emerging mechanisms of targeted protein degradation by molecular glues
PubMed | Feburary 2022
4. Defining molecular glues with a dual-nanobody cannabidiol sensor
PubMed | July 2021
5. Molecular glues for targeted protein degradation: From serendipity to rational discovery
PubMed | April 2021
6. Haven’t got a glue: Protein surface variation for the design of molecular glue degraders
PubMed | January 2021
7. The rise of molecular glues
Targeted Protein Degradation:
PubMed | March 2022
1. Driving E3 ligase substrate specificity for targeted protein degradation: Lessons from nature to the laboratory
PubMed | February 2021
2. Rationalizing PROTAC-mediated ternary complex formation using Rosetta
Annual Reviews | December 2020
3. Small-molecule approaches to targeted protein degradation
Artificial intelligence (AI) in drug discovery:
PubMed | March 2022
1. Design of protein binding proteins from target structure alone
PubMed | December 2021
2. Computed structures of core eukaryotic protein complexes
Annual Reviews | December 2019
3. Machine learning for protein folding and dynamics