Senior Scientist, Lead Discovery

Description

About TRIANA Biomedicines: 

TRIANA Biomedicines is a Greater Boston biotechnology company building the leading molecular glue discovery platform to regulate disease targets that are difficult to address with any other modality. TRIANA’s drug discovery engine is powered by high-resolution structural insights, state-of-the-art AI and computational tools, and bespoke chemical libraries. TRIANA’s target-first and rational approach to molecular glue discovery is currently focused on inducing or enhancing the degradation of high-profile cancer targets. The therapeutic approach pioneered by TRIANA has the potential to fundamentally change the paradigm of small molecule drug discovery and bring significant therapeutic benefits to patients. TRIANA is a private company with a top-tier investor syndicate.

Responsibilities:

The successful candidate will play a key role in TRIANA Biomedicine’s lead discovery efforts, leveraging our novel discovery platform to pursue high‑value disease targets. In this role, you will design, develop, and execute cellular and biochemical assays that drive early-stage molecular glue discovery.

As a central member of a highly matrixed research team, you will help shape the data packages that advance early hits into our therapeutic pipeline. This position offers the opportunity to influence scientific direction as both a hands‑on bench scientist and an internal thought leader.

We are seeking a candidate who thrives in a fast‑paced, innovative environment and is energized by close collaboration across diverse scientific disciplines including chemistry, biology, and informatics. If you are excited by the prospect of building and applying cutting‑edge discovery approaches to transform therapeutic possibilities, we’d love to speak with you.

Qualifications:

• Ph.D. in Molecular Biology, Biochemistry, Cell Biology, Chemical Biology, or a related field (5+ years of experience); or M.S./B.S. with significant industry experience (12+ years of experience).

• Demonstrated expertise in cellular and/or biochemical assay development and execution.

• Strong background in mechanism‑of‑action studies, biophysics, target validation, or early drug discovery.

• Proven ability to work effectively in a fast-paced, multidisciplinary research environments.

• Excellent communication and data presentation skills.

Preferred:

• Experience with targeted protein degradation, molecular glue mechanisms, or related modalities.

• Core expertise in oncology with experience in immunology therapeutic discovery a strong plus

• Familiarity with high‑throughput screening, automation, or complex assay platforms.

• Experience managing or mentoring junior scientists is a plus

Base Salary Range: $145k-$155k

We welcome applications from skilled individuals whose qualifications may not fit the criteria outlined above.

Our Culture: 

Our Team is our greatest asset at TRIANA. We are proud to work with an integrated group of individuals from an extensive range of backgrounds and experiences. Diversity, Equity, Inclusion and Belonging are important aspects of our culture. We embrace our differences and cultivate an environment that drives better collaboration and innovation by striving to ensure that all coworkers have an ongoing positive experience while being their authentic selves. 

Our Values: 

At TRIANA we are empowered to act. We dare to create transformative medicines for patients. Our creativity and dedication are the glue that unites us in pursuit of our mission. 

Thank you for your interest in TRIANA!

Qualifying candidates should apply here

TRIANA Biomedicines is an Equal Opportunity Employer take great pride in creating a diverse employment environment.

TRIANA Biomedicines does not accept unsolicited resumes from search firms for listed employment opportunities. All unsolicited resumes/CVs submitted through our website or to personal e-mail accounts of employees of TRIANA shall be deemed property of TRIANA. TRIANA explicitly reserves the right to pursue and hire those candidates without any financial obligation to the recruiter or search firm.