Scientist, Biology and Translational Sciences

Description

About TRIANA Biomedicines: 

TRIANA’s target-first and rational approach to molecular glue discovery is currently focused on inducing or enhancing the degradation of high-profile cancer targets. TRIANA Biomedicines is a Greater Boston biotechnology company building the leading molecular glue discovery platform to regulate disease targets that are difficult to address with any other modality. TRIANA’s drug discovery engine is powered by high-resolution structural insights, state-of-the-art AI and computational tools, and bespoke chemical libraries. The therapeutic approach pioneered by TRIANA has the potential to fundamentally change the paradigm of small molecule drug discovery and bring significant therapeutic benefits to patients. TRIANA is a private company with a top-tier investor syndicate. 

Role: 

The Biology and Translational Sciences group at TRIANA Biomedicines is seeking a passionate and independent scientist to help drive pre-portfolio activities to populate an expanding pipeline of high value oncology targets. The qualified candidate will join a growing team of dedicated researchers seeking to deliver on TRIANA’s target-first approach to molecular glue discovery. 

Responsibilities:

• Use genetic and chemical tools to evaluate the protein turnover mechanisms of high value oncology targets 

• Optimize proximity-based methods to identify target/effector pairs for glue discovery 

• Partner with colleagues in Lead Discovery to design and develop cell-based assays for molecular glue discovery 

• Interrogate cellular mechanism of action of novel glues in disease-relevant assay systems 

• Record, interpret, and communicate data promptly  

• Present data in cross-functional project team meetings 

 Qualifications:

• Solid bench skillset with hands-on experience in molecular and cell biology techniques such as cell culture, CRISPR, RNAi, transfection, lentiviral transduction, immunoprecipitation, immunoblotting, qRT-PCR, and cell proliferation/viability assays 

• Solid verbal and writing skills for data documentation, drafting reports and communication to team members 

• Team-oriented, flexible, independent, enthusiastic, and collaborative  

Education/experience:  

Ph.D. in Cell or Molecular Biology or related discipline with 0-3+ years of post-graduate experience (industry preferred), or BS/MS with 5+ years of industry experience 

We welcome applications from skilled individuals whose qualifications may not fit the criteria outlined above. 

Our Culture: 

Our Team is our greatest asset at TRIANA. We are proud to work with an integrated group of individuals from an extensive range of backgrounds and experiences. Diversity, Equity, Inclusion and Belonging are important aspects of our culture. We embrace our differences and cultivate an environment that drives better collaboration and innovation by striving to ensure that all coworkers have an ongoing positive experience while being their authentic selves. 

Our Values: 

At TRIANA we are empowered to act. We dare to create transformative medicines for patients. Our creativity and dedication are the glue that unites us in pursuit of our mission. 

Thank you for your interest in TRIANA!

Qualifying candidates should apply here

TRIANA Biomedicines is an Equal Opportunity Employer take great pride in creating a diverse employment environment.

TRIANA Biomedicines does not accept unsolicited resumes from search firms for listed employment opportunities. All unsolicited resumes/CVs submitted through our website or to personal e-mail accounts of employees of TRIANA shall be deemed property of TRIANA. TRIANA explicitly reserves the right to pursue and hire those candidates without any financial obligation to the recruiter or search firm.